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Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation.
Trefely, Sophie; Huber, Katharina; Liu, Joyce; Noji, Michael; Stransky, Stephanie; Singh, Jay; Doan, Mary T; Lovell, Claudia D; von Krusenstiern, Eliana; Jiang, Helen; Bostwick, Anna; Pepper, Hannah L; Izzo, Luke; Zhao, Steven; Xu, Jimmy P; Bedi, Kenneth C; Rame, J Eduardo; Bogner-Strauss, Juliane G; Mesaros, Clementina; Sidoli, Simone; Wellen, Kathryn E; Snyder, Nathaniel W.
Afiliación
  • Trefely S; Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104,
  • Huber K; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute of Biochemistry, Graz University of Technology, Graz 8010, Austria.
  • Liu J; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA; Biochemistry and Molecular Biophysics Graduate Group, Perelman School of Medicine, University of Pennsylvania, Ph
  • Noji M; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA; Cell and Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia,
  • Stransky S; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Singh J; Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
  • Doan MT; Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
  • Lovell CD; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA; Cell and Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia,
  • von Krusenstiern E; Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
  • Jiang H; Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
  • Bostwick A; Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
  • Pepper HL; Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
  • Izzo L; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA; Cell and Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia,
  • Zhao S; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA; Cell and Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia,
  • Xu JP; Department of Pharmacology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Bedi KC; Penn Medicine Heart Failure Mechanical Assist and Cardiac Transplant Center, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Rame JE; Penn Medicine Heart Failure Mechanical Assist and Cardiac Transplant Center, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Bogner-Strauss JG; Institute of Biochemistry, Graz University of Technology, Graz 8010, Austria.
  • Mesaros C; Department of Pharmacology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Sidoli S; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Wellen KE; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA; Penn Epigenetics Institute, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: wellenk@
  • Snyder NW; Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA. Electronic address: natewsnyder@temple.edu.
Mol Cell ; 82(2): 447-462.e6, 2022 01 20.
Article en En | MEDLINE | ID: mdl-34856123
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Acilcoenzima A / Histonas / Compartimento Celular / Núcleo Celular / Procesamiento Proteico-Postraduccional / Metabolismo Energético / Metabolómica Tipo de estudio: Prognostic_studies Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Acilcoenzima A / Histonas / Compartimento Celular / Núcleo Celular / Procesamiento Proteico-Postraduccional / Metabolismo Energético / Metabolómica Tipo de estudio: Prognostic_studies Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article