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Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands.
Linossi, Edmond M; Li, Kunlun; Veggiani, Gianluca; Tan, Cyrus; Dehkhoda, Farhad; Hockings, Colin; Calleja, Dale J; Keating, Narelle; Feltham, Rebecca; Brooks, Andrew J; Li, Shawn S; Sidhu, Sachdev S; Babon, Jeffrey J; Kershaw, Nadia J; Nicholson, Sandra E.
Afiliación
  • Linossi EM; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Li K; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
  • Veggiani G; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Tan C; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
  • Dehkhoda F; The Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.
  • Hockings C; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Calleja DJ; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
  • Keating N; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Feltham R; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
  • Brooks AJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Li SS; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
  • Sidhu SS; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Babon JJ; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
  • Kershaw NJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Nicholson SE; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
Nat Commun ; 12(1): 7032, 2021 12 02.
Article en En | MEDLINE | ID: mdl-34857742
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Tirosina / Proteínas Supresoras de la Señalización de Citocinas Tipo de estudio: Prognostic_studies Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Tirosina / Proteínas Supresoras de la Señalización de Citocinas Tipo de estudio: Prognostic_studies Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article