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Kynurenine induces T cell fat catabolism and has limited suppressive effects in vivo.
Siska, Peter J; Jiao, Jing; Matos, Carina; Singer, Katrin; Berger, Raffaela S; Dettmer, Katja; Oefner, Peter J; Cully, Michelle D; Wang, Zhonglin; QuinnIII, William J; Oliff, Kristen N; Wilkins, Benjamin J; Christensen, Lanette M; Wang, Liqing; Hancock, Wayne W; Baur, Joseph A; Levine, Matthew H; Ugele, Ines; Mayr, Roman; Renner, Kathrin; Zhou, Liang; Kreutz, Marina; Beier, Ulf H.
Afiliación
  • Siska PJ; Department of Internal Medicine III, University Hospital Regensburg, 93053 Regensburg, Germany.
  • Jiao J; Division of Nephrology, Department of Pediatrics, Children's Hospital of Philadelphia, and University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Matos C; Department of Internal Medicine III, University Hospital Regensburg, 93053 Regensburg, Germany.
  • Singer K; Department of Otorhinolaryngology, University Hospital Regensburg, 93053 Regensburg, Germany.
  • Berger RS; Institute of Functional Genomics, University of Regensburg, 93053 Regensburg, Germany.
  • Dettmer K; Institute of Functional Genomics, University of Regensburg, 93053 Regensburg, Germany.
  • Oefner PJ; Institute of Functional Genomics, University of Regensburg, 93053 Regensburg, Germany.
  • Cully MD; Division of Nephrology, Department of Pediatrics, Children's Hospital of Philadelphia, and University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Wang Z; Department of Surgery, Penn Transplant Institute, Perelman School of Medicine, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA 19104, USA.
  • QuinnIII WJ; Department of Physiology and Institute of Diabetes, Obesity, and Metabolism, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Oliff KN; Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL 32608, USA.
  • Wilkins BJ; Division of Anatomic Pathology, Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104 USA.
  • Christensen LM; Division of Transplant Immunology, Department of Pathology and Laboratory Medicine, and Biesecker Center for Pediatric Liver Disease, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Wang L; Division of Transplant Immunology, Department of Pathology and Laboratory Medicine, and Biesecker Center for Pediatric Liver Disease, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Hancock WW; Division of Transplant Immunology, Department of Pathology and Laboratory Medicine, and Biesecker Center for Pediatric Liver Disease, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Baur JA; Department of Physiology and Institute of Diabetes, Obesity, and Metabolism, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Levine MH; Department of Surgery, Penn Transplant Institute, Perelman School of Medicine, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Ugele I; Department of Otorhinolaryngology, University Hospital Regensburg, 93053 Regensburg, Germany.
  • Mayr R; Department of Urology, Caritas St. Josef Medical Centre, University of Regensburg, Regensburg, Germany.
  • Renner K; Department of Internal Medicine III, University Hospital Regensburg, 93053 Regensburg, Germany; Regensburg Center for Interventional Immunology, University of Regensburg, 93053 Regensburg, Germany.
  • Zhou L; Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL 32608, USA.
  • Kreutz M; Department of Internal Medicine III, University Hospital Regensburg, 93053 Regensburg, Germany; Regensburg Center for Interventional Immunology, University of Regensburg, 93053 Regensburg, Germany.
  • Beier UH; Division of Nephrology, Department of Pediatrics, Children's Hospital of Philadelphia, and University of Pennsylvania, Philadelphia, PA 19104, USA; Current affiliation: Janssen Research and Development, Spring House, 19477 PA, USA. Electronic address: ubeier@its.jnj.com.
EBioMedicine ; 74: 103734, 2021 Dec.
Article en En | MEDLINE | ID: mdl-34875457
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Melanoma Experimental / Linfocitos T / Colitis / Proteínas de Homeodominio / Ácidos Grasos / Inmunosupresores / Quinurenina Tipo de estudio: Prognostic_studies Idioma: En Revista: EBioMedicine Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Melanoma Experimental / Linfocitos T / Colitis / Proteínas de Homeodominio / Ácidos Grasos / Inmunosupresores / Quinurenina Tipo de estudio: Prognostic_studies Idioma: En Revista: EBioMedicine Año: 2021 Tipo del documento: Article