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Precipitate-Supported Thermal Proteome Profiling Coupled with Deep Learning for Comprehensive Screening of Drug Target Proteins.
Ruan, Chengfei; Ning, Wanshan; Liu, Zhen; Zhang, Xiaolei; Fang, Zheng; Li, Yanan; Dang, Yongjun; Xue, Yu; Ye, Mingliang.
Afiliación
  • Ruan C; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Dalian 116023, China.
  • Ning W; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Liu Z; MOE Key Laboratory of Molecular Biophysics, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and Technology (HUST), Wuhan, Hubei 430074, China.
  • Zhang X; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Dalian 116023, China.
  • Fang Z; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Dalian 116023, China.
  • Li Y; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Dalian 116023, China.
  • Dang Y; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Xue Y; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Dalian 116023, China.
  • Ye M; Center for Novel Target and Therapeutic Intervention, Institute of Life Sciences, Chongqing Medical University, Chongqing 400016, China.
ACS Chem Biol ; 17(1): 252-262, 2022 01 21.
Article en En | MEDLINE | ID: mdl-34989232
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Precipitación Química / Proteínas / Sistemas de Liberación de Medicamentos / Proteoma / Proteómica / Aprendizaje Profundo Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: ACS Chem Biol Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Precipitación Química / Proteínas / Sistemas de Liberación de Medicamentos / Proteoma / Proteómica / Aprendizaje Profundo Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: ACS Chem Biol Año: 2022 Tipo del documento: Article