An Approach to the Patient With Delayed Puberty.
J Clin Endocrinol Metab
; 107(6): 1739-1750, 2022 05 17.
Article
en En
| MEDLINE
| ID: mdl-35100608
ABSTRACT
Pediatric endocrinologists often evaluate and treat youth with delayed puberty. Stereotypically, these patients are 14-year-old young men who present due to lack of pubertal development. Concerns about stature are often present, arising from gradual shifts to lower height percentiles on the population-based, cross-sectional curves. Fathers and/or mothers may have also experienced later than average pubertal onset. In this review, we will discuss a practical clinical approach to the evaluation and management of youth with delayed puberty, including the differential diagnosis and key aspects of evaluation and management informed by recent review of the existing literature. We will also discuss scenarios that pose additional clinical challenges, including (1) the young woman whose case poses questions regarding how presentation and approach differs for females vs males; (2) the 14-year-old female or 16-year-old young man who highlight the need to reconsider the most likely diagnoses, including whether idiopathic delayed puberty can still be considered constitutional delay of growth and puberty at such late ages; and finally (3) the 12- to 13-year-old whose presentation raises questions about whether age cutoffs for the diagnosis and treatment of delayed puberty should be adjusted downward to coincide with the earlier onset of puberty in the general population.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Pubertad Tardía
/
Hipogonadismo
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
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Observational_studies
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Prevalence_studies
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Risk_factors_studies
Idioma:
En
Revista:
J Clin Endocrinol Metab
Año:
2022
Tipo del documento:
Article