Your browser doesn't support javascript.
loading
Molecular Prosthetics for Long-Term Functional Imaging with Fluorescent Reporters.
Grenier, Vincent; Martinez, Kayli N; Benlian, Brittany R; García-Almedina, Derek M; Raliski, Benjamin K; Boggess, Steven C; Maza, Johnathan C; Yang, Samantha J; Gest, Anneliese M M; Miller, Evan W.
Afiliación
  • Grenier V; Department of Chemistry and Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute. University of California, Berkeley, California 94720, United States.
  • Martinez KN; Department of Chemistry and Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute. University of California, Berkeley, California 94720, United States.
  • Benlian BR; Department of Chemistry and Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute. University of California, Berkeley, California 94720, United States.
  • García-Almedina DM; Department of Chemistry and Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute. University of California, Berkeley, California 94720, United States.
  • Raliski BK; Department of Chemistry and Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute. University of California, Berkeley, California 94720, United States.
  • Boggess SC; Department of Chemistry and Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute. University of California, Berkeley, California 94720, United States.
  • Maza JC; Department of Chemistry and Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute. University of California, Berkeley, California 94720, United States.
  • Yang SJ; Department of Chemistry and Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute. University of California, Berkeley, California 94720, United States.
  • Gest AMM; Department of Chemistry and Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute. University of California, Berkeley, California 94720, United States.
  • Miller EW; Department of Chemistry and Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute. University of California, Berkeley, California 94720, United States.
ACS Cent Sci ; 8(1): 118-121, 2022 Jan 26.
Article en En | MEDLINE | ID: mdl-35111902
Voltage-sensitive fluorescent reporters can reveal fast changes in the membrane potential in neurons and cardiomyocytes. However, in many cases, illumination in the presence of the fluorescent reporters results in disruptions to the action potential shape that limits the length of recording sessions. We show here that a molecular prosthetic approach, previously limited to fluorophores, rather than indicators, can be used to substantially prolong imaging in neurons and cardiomyocytes.
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: ACS Cent Sci Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: ACS Cent Sci Año: 2022 Tipo del documento: Article