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Do biometric parameters improve the quality of optic nerve head measurements with spectral domain optical coherence tomography?
Elksne, E; Stingl, J V; Schuster, A K; Wagner, F M; Hoffmann, E M.
Afiliación
  • Elksne E; Department of Ophthalmology, Riga Stradins University, Dzirciema iela 16, Riga, 1007, Latvia.
  • Stingl JV; Department of Ophthalmology, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.
  • Schuster AK; Department of Ophthalmology, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.
  • Wagner FM; Department of Ophthalmology, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.
  • Hoffmann EM; Department of Ophthalmology, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany. ehoffman@uni-mainz.de.
BMC Ophthalmol ; 22(1): 56, 2022 Feb 05.
Article en En | MEDLINE | ID: mdl-35123423
ABSTRACT

BACKGROUND:

Spectral domain optical coherence tomography (SD-OCT) is a widely applied non-invasive technique for evaluating optic nerve head parameters. The aim of this study was to evaluate the impact of biometric parameters such as the spherical equivalent (SE) and the anterior corneal curvature (ACC) on the peripapillary retinal nerve fiber layer (pRNFL), Bruch's membrane opening (BMO), and the minimum rim width (MRW) measurements performed by spectral domain optical coherence tomography (SD-OCT) in glaucomatous and healthy eyes.

METHODS:

In this cross-sectional, case-control prospective pilot study, the glaucoma group consisted of 50 patients with previously diagnosed and treated glaucoma and one healthy group of 50 subjects. Two consecutive examinations of pRNFL, BMO, and MRW with SD-OCT for every patient were performed without ACC and objective refraction (imaging 1) and with them (imaging 2).

RESULTS:

The interclass correlation coefficient (ICC) reflected high agreement between imaging 1 and imaging 2 in both groups. The ICC in the glaucoma and healthy groups for pRNFL (0.99 vs. 0.98), BMO (0.95 vs. 0.97), and MRW (1.0 vs. 1.0) was comparable.

CONCLUSIONS:

Our preliminary data from a small number of eyes showed that the measurements of pRNFL, MRW, and BMO reflected high agreement between both imaging techniques with ACC and objective refraction and without these parameters in subjects with a refractive error up to ± 6.0 diopters. Further studies with participants with higher refractive error are necessary to evaluate the impact of biometric parameters such as SE and ACC on measurements with SD-OCT.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Disco Óptico Tipo de estudio: Observational_studies / Prevalence_studies / Risk_factors_studies Idioma: En Revista: BMC Ophthalmol Asunto de la revista: OFTALMOLOGIA Año: 2022 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Disco Óptico Tipo de estudio: Observational_studies / Prevalence_studies / Risk_factors_studies Idioma: En Revista: BMC Ophthalmol Asunto de la revista: OFTALMOLOGIA Año: 2022 Tipo del documento: Article