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Discovery of novel rigid analogs of 2-naphthol with potent anticancer activity through multi-target topoisomerase I & II and tyrosine kinase receptor EGFR & VEGFR-2 inhibition mechanism.
El-Mawgoud, Heba K A; Fouda, Ahmed M; El-Nassag, Mohammed A A; Elhenawy, Ahmed A; Alshahrani, Mohammed Y; El-Agrody, Ahmed M.
Afiliación
  • El-Mawgoud HKA; Chemistry Department, Faculty of Women for Arts, Science, and Education, Ain Shams University, Heliopolis, Cairo, 11757, Egypt.
  • Fouda AM; Chemistry Department, Faculty of Science, King Khalid University, Abha, 61413, Saudi Arabia.
  • El-Nassag MAA; Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City, 11884, Cairo, Egypt; Chemistry Department, Faculty of Science, Jazan University, Jazan, 45142, Saudi Arabia.
  • Elhenawy AA; Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City, 11884, Cairo, Egypt; Chemistry Department, Faculty of Science and Art, AlBaha University, Mukhwah, AlBaha, Saudi Arabia. Electronic address: elhenawy_sci@hotmail.com.
  • Alshahrani MY; Department of Clinical Laboratory Science, College of Applied Medical Science, King Khalid University, Abha 61413, 9088, Saudi Arabia.
  • El-Agrody AM; Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City, 11884, Cairo, Egypt.
Chem Biol Interact ; 355: 109838, 2022 Mar 01.
Article en En | MEDLINE | ID: mdl-35123995
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: ADN-Topoisomerasas de Tipo II / ADN-Topoisomerasas de Tipo I / Receptor 2 de Factores de Crecimiento Endotelial Vascular / Receptores ErbB / Naftoles / Antineoplásicos Tipo de estudio: Prognostic_studies Idioma: En Revista: Chem Biol Interact Año: 2022 Tipo del documento: Article
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: ADN-Topoisomerasas de Tipo II / ADN-Topoisomerasas de Tipo I / Receptor 2 de Factores de Crecimiento Endotelial Vascular / Receptores ErbB / Naftoles / Antineoplásicos Tipo de estudio: Prognostic_studies Idioma: En Revista: Chem Biol Interact Año: 2022 Tipo del documento: Article