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PD-L1 promotes myofibroblastic activation of hepatic stellate cells by distinct mechanisms selective for TGF-ß receptor I versus II.
Sun, Liankang; Wang, Yuanguo; Wang, Xianghu; Navarro-Corcuera, Amaia; Ilyas, Sumera; Jalan-Sakrikar, Nidhi; Gan, Can; Tu, Xinyi; Shi, Yu; Tu, Kangsheng; Liu, Qingguang; Lou, Zhenkun; Dong, Haidong; Sharpe, Arlene H; Shah, Vijay H; Kang, Ningling.
Afiliación
  • Sun L; GI Research Unit and Cancer Cell Biology Program, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 1(st) ST SW, Rochester, MN 55905, USA.
  • Wang Y; Tumor Microenvironment and Metastasis, the Hormel Institute, University of Minnesota, 801 16(th) Ave NE, Austin, MN 55912, USA.
  • Wang X; Tumor Microenvironment and Metastasis, the Hormel Institute, University of Minnesota, 801 16(th) Ave NE, Austin, MN 55912, USA.
  • Navarro-Corcuera A; GI Research Unit and Cancer Cell Biology Program, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 1(st) ST SW, Rochester, MN 55905, USA.
  • Ilyas S; GI Research Unit and Cancer Cell Biology Program, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 1(st) ST SW, Rochester, MN 55905, USA.
  • Jalan-Sakrikar N; GI Research Unit and Cancer Cell Biology Program, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 1(st) ST SW, Rochester, MN 55905, USA.
  • Gan C; GI Research Unit and Cancer Cell Biology Program, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 1(st) ST SW, Rochester, MN 55905, USA.
  • Tu X; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.
  • Shi Y; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.
  • Tu K; Department of Hepatobiliary Surgery, 1st Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, P.R. China.
  • Liu Q; Department of Hepatobiliary Surgery, 1st Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, P.R. China.
  • Lou Z; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.
  • Dong H; Department of Urology, Mayo Clinic, Rochester, MN 55905, USA; Department of Immunology, Mayo Clinic, Rochester, MN 55905, USA.
  • Sharpe AH; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
  • Shah VH; GI Research Unit and Cancer Cell Biology Program, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 1(st) ST SW, Rochester, MN 55905, USA. Electronic address: shah.vijay@mayo.edu.
  • Kang N; Tumor Microenvironment and Metastasis, the Hormel Institute, University of Minnesota, 801 16(th) Ave NE, Austin, MN 55912, USA. Electronic address: nkang@umn.edu.
Cell Rep ; 38(6): 110349, 2022 02 08.
Article en En | MEDLINE | ID: mdl-35139382

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Células Estrelladas Hepáticas / Miofibroblastos / Antígeno B7-H1 / Receptor Tipo I de Factor de Crecimiento Transformador beta / Neoplasias Hepáticas Idioma: En Revista: Cell Rep Año: 2022 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Células Estrelladas Hepáticas / Miofibroblastos / Antígeno B7-H1 / Receptor Tipo I de Factor de Crecimiento Transformador beta / Neoplasias Hepáticas Idioma: En Revista: Cell Rep Año: 2022 Tipo del documento: Article