UHMK1-dependent phosphorylation of Cajal body protein coilin alters 5-FU sensitivity in colon cancer cells.

Niu, Huan; Zhao, Meng; Huang, Jing; Wang, Jing; Si, Yang; Cheng, Shan; Ding, Wei

Niu, Huan; Zhao, Meng; Huang, Jing; Wang, Jing; Si, Yang; Cheng, Shan; Ding, Wei.

Afiliación

Niu H; Department of Medical Genetics and Developmental Biology, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.
Zhao M; Department of Thoracic Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Huang J; Department of Medical Genetics and Developmental Biology, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.
Wang J; Department of Medical Genetics and Developmental Biology, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.
Si Y; Department of Medical Genetics and Developmental Biology, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.
Cheng S; Department of Medical Genetics and Developmental Biology, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China. chengs@ccmu.edu.cn.
Ding W; Department of Medical Genetics and Developmental Biology, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.

Cell Commun Signal ; 20(1): 18, 2022 02 12.

Article en En | MEDLINE | ID: mdl-35151311

Asunto(s)

Cuerpos Enrollados; Neoplasias del Colon; Fluorouracilo; Péptidos y Proteínas de Señalización Intracelular; Proteínas Serina-Treonina Quinasas; Antimetabolitos Antineoplásicos/farmacología; Cuerpos Enrollados/efectos de los fármacos; Cuerpos Enrollados/genética; Cuerpos Enrollados/metabolismo; Fluorouracilo/farmacología; Humanos; Péptidos y Proteínas de Señalización Intracelular/metabolismo; Proteínas Nucleares/metabolismo; Fosforilación/efectos de los fármacos; Proteínas Serina-Treonina Quinasas/metabolismo; Microambiente Tumoral

Palabras clave

5-FU resistance; Cajal body; Coilin; Colon cancer; UHMK1

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Serina-Treonina Quinasas / Neoplasias del Colon / Cuerpos Enrollados / Péptidos y Proteínas de Señalización Intracelular / Fluorouracilo Tipo de estudio: Diagnostic_studies Idioma: En Revista: Cell Commun Signal Año: 2022 Tipo del documento: Article

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