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Improved therapeutic index of an acidic pH-selective antibody.
Lee, Peter S; MacDonald, Katherine G; Massi, Evan; Chew, Pamela V; Bee, Christine; Perkins, Padma; Chau, Bryant; Thudium, Kent; Lohre, Jack; Nandi, Pradyot; Deyanova, Ekaterina G; Barman, Ishita; Gudmundsson, Olafur; Dollinger, Gavin; Sproul, Tim; Engelhardt, John J; Strop, Pavel; Rajpal, Arvind.
Afiliación
  • Lee PS; Discovery Biotherapeutics, Bristol Myers Squibb, Redwood City, CA, USA.
  • MacDonald KG; Immuno-Oncology Research, Bristol Myers Squibb, Redwood City, CA, USA.
  • Massi E; Immuno-Oncology Research, Bristol Myers Squibb, Redwood City, CA, USA.
  • Chew PV; Oncology Biology, Gilead Sciences, Foster City, CA, USA.
  • Bee C; Discovery Biology, Frontier Medicines, South San Francisco, CA, USA.
  • Perkins P; Immuno-Oncology Research, Bristol Myers Squibb, Redwood City, CA, USA.
  • Chau B; Kyverna, Synthetic Biology, Emeryville, CA, USA.
  • Thudium K; Immuno-Oncology Research, Bristol Myers Squibb, Redwood City, CA, USA.
  • Lohre J; In Vivo Pharmacology, Bristol Myers Squibb, Redwood City, CA, USA.
  • Nandi P; Pharmaceutical Candidate Optimization, Bristol Myers Squibb, Lawrenceville, NJ, USA.
  • Deyanova EG; Pharmaceutical Candidate Optimization, Bristol Myers Squibb, Lawrenceville, NJ, USA.
  • Barman I; Therapeutic Discovery, 3T Biosciences, South San Francisco, CA, USA.
  • Gudmundsson O; Pharmaceutical Candidate Optimization, Bristol Myers Squibb, Lawrenceville, NJ, USA.
  • Dollinger G; Discovery Biotherapeutics, Bristol Myers Squibb, Redwood City, CA, USA.
  • Sproul T; In Vivo Pharmacology, UNITY Biotechnology, South San Francisco, CA, USA.
  • Engelhardt JJ; Immuno-Oncology Discovery, Abbvie, South San Francisco, CA, USA.
  • Strop P; Biologics Discovery, Tallac Therapeutics, Burlingame, CA, USA.
  • Rajpal A; Large Molecule Drug Discovery, Genentech Research and Early Development, South San Francisco, CA, USA.
MAbs ; 14(1): 2024642, 2022.
Article en En | MEDLINE | ID: mdl-35192429
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Microambiente Tumoral / Neoplasias Idioma: En Revista: MAbs Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Microambiente Tumoral / Neoplasias Idioma: En Revista: MAbs Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2022 Tipo del documento: Article