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The functional impact of BRCA1 BRCT domain variants using multiplexed DNA double-strand break repair assays.
Adamovich, Aleksandra I; Diabate, Mariame; Banerjee, Tapahsama; Nagy, Gregory; Smith, Nahum; Duncan, Kathryn; Mendoza Mendoza, Erika; Prida, Gisselle; Freitas, Michael A; Starita, Lea M; Parvin, Jeffrey D.
Afiliación
  • Adamovich AI; Department of Biomedical Informatics, The Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA.
  • Diabate M; Department of Biomedical Informatics, The Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA.
  • Banerjee T; Department of Biomedical Informatics, The Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA.
  • Nagy G; Department of Biomedical Informatics, The Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA.
  • Smith N; Department of Genome Sciences, University of Washington and Brotman Baty Institute for Precision Medicine, Seattle, WA 98195, USA.
  • Duncan K; Department of Biomedical Informatics, The Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA.
  • Mendoza Mendoza E; Department of Biomedical Informatics, The Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA.
  • Prida G; Department of Biomedical Informatics, The Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA.
  • Freitas MA; Department of Cancer Biology and Genetics, The Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA.
  • Starita LM; Department of Genome Sciences, University of Washington and Brotman Baty Institute for Precision Medicine, Seattle, WA 98195, USA.
  • Parvin JD; Department of Biomedical Informatics, The Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA. Electronic address: jeffrey.parvin@osumc.edu.
Am J Hum Genet ; 109(4): 618-630, 2022 04 07.
Article en En | MEDLINE | ID: mdl-35196514
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Proteína BRCA1 / Roturas del ADN de Doble Cadena Idioma: En Revista: Am J Hum Genet Año: 2022 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Proteína BRCA1 / Roturas del ADN de Doble Cadena Idioma: En Revista: Am J Hum Genet Año: 2022 Tipo del documento: Article