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A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine.
Sebastian, Carlos; Ferrer, Christina; Serra, Maria; Choi, Jee-Eun; Ducano, Nadia; Mira, Alessia; Shah, Manasvi S; Stopka, Sylwia A; Perciaccante, Andrew J; Isella, Claudio; Moya-Rull, Daniel; Vara-Messler, Marianela; Giordano, Silvia; Maldi, Elena; Desai, Niyati; Capen, Diane E; Medico, Enzo; Cetinbas, Murat; Sadreyev, Ruslan I; Brown, Dennis; Rivera, Miguel N; Sapino, Anna; Breault, David T; Agar, Nathalie Y R; Mostoslavsky, Raul.
Afiliación
  • Sebastian C; Candiolo Cancer Institute-FPO, IRCCS, Candiolo, 10060, Italy. csebastian@ub.edu.
  • Ferrer C; Departament de Biologia Cel.lular, Fisiologia i Immunologia, Facultad de Biologia, Universitat de Barcelona (UB), 08028, Barcelona, Spain. csebastian@ub.edu.
  • Serra M; Institut de Biomedicina de la Universitat de Barcelona (IBUB), 08028, Barcelona, Spain. csebastian@ub.edu.
  • Choi JE; The Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, 02114, USA.
  • Ducano N; The MGH Center for Regenerative Medicine, Harvard Medical School, Boston, MA, 02114, USA.
  • Mira A; Candiolo Cancer Institute-FPO, IRCCS, Candiolo, 10060, Italy.
  • Shah MS; The Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, 02114, USA.
  • Stopka SA; The MGH Center for Regenerative Medicine, Harvard Medical School, Boston, MA, 02114, USA.
  • Perciaccante AJ; Candiolo Cancer Institute-FPO, IRCCS, Candiolo, 10060, Italy.
  • Isella C; Candiolo Cancer Institute-FPO, IRCCS, Candiolo, 10060, Italy.
  • Moya-Rull D; Division of Endocrinology, Boston Children's Hospital, Boston, MA, 02115, USA.
  • Vara-Messler M; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Giordano S; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Maldi E; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Desai N; University of Georgia, Athens, GA, USA.
  • Capen DE; Candiolo Cancer Institute-FPO, IRCCS, Candiolo, 10060, Italy.
  • Medico E; Department of Oncology, University of Torino, Turin, Italy.
  • Cetinbas M; Candiolo Cancer Institute-FPO, IRCCS, Candiolo, 10060, Italy.
  • Sadreyev RI; Department of Oncology, University of Torino, Turin, Italy.
  • Brown D; Department of Oncology, University of Torino, Turin, Italy.
  • Rivera MN; Pole of Pharmacology and Therapeutics (FATH), Institut de Recherche Experimentale et Clinique (IREC), UCLeuven, Brussels, Belgium.
  • Sapino A; Candiolo Cancer Institute-FPO, IRCCS, Candiolo, 10060, Italy.
  • Breault DT; Department of Oncology, University of Torino, Turin, Italy.
  • Agar NYR; Candiolo Cancer Institute-FPO, IRCCS, Candiolo, 10060, Italy.
  • Mostoslavsky R; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.
Nat Commun ; 13(1): 1503, 2022 03 21.
Article en En | MEDLINE | ID: mdl-35314684
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Sirtuinas / Neoplasias Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article
Texto completo
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XML
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Sirtuinas / Neoplasias Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article