Acute Myeloid Leukemia Cells Functionally Compromise Hematopoietic Stem/Progenitor Cells Inhibiting Normal Hematopoiesis Through the Release of Extracellular Vesicles.

Trino, Stefania; Laurenzana, Ilaria; Lamorte, Daniela; Calice, Giovanni; De Stradis, Angelo; Santodirocco, Michele; Sgambato, Alessandro; Caivano, Antonella; De Luca, Luciana

Trino, Stefania; Laurenzana, Ilaria; Lamorte, Daniela; Calice, Giovanni; De Stradis, Angelo; Santodirocco, Michele; Sgambato, Alessandro; Caivano, Antonella; De Luca, Luciana.

Afiliación

Trino S; Laboratory of Preclinical and Translational Research, Centro di Riferimento Oncologico della Basilicata (IRCCS-CROB), Rionero in Vulture, Italy.
Laurenzana I; Laboratory of Preclinical and Translational Research, Centro di Riferimento Oncologico della Basilicata (IRCCS-CROB), Rionero in Vulture, Italy.
Lamorte D; Laboratory of Preclinical and Translational Research, Centro di Riferimento Oncologico della Basilicata (IRCCS-CROB), Rionero in Vulture, Italy.
Calice G; Laboratory of Preclinical and Translational Research, Centro di Riferimento Oncologico della Basilicata (IRCCS-CROB), Rionero in Vulture, Italy.
De Stradis A; Institute for Sustainable Plant Protection, National Research Council (CNR), Bari, Italy.
Santodirocco M; Trasfusional Medicine Department, Puglia Cord Blood Bank (CBB), Casa Sollievo Della Sofferenza Hospital, San Giovanni Rotondo, Italy.
Sgambato A; Scientific Direction, Centro di Riferimento Oncologico della Basilicata (IRCCS-CROB), Rionero in Vulture, Italy.
Caivano A; Unit of Clinical Pathology, Centro di Riferimento Oncologico della Basilicata (IRCCS-CROB), Rionero in Vulture, Italy.
De Luca L; Unit of Clinical Pathology, Centro di Riferimento Oncologico della Basilicata (IRCCS-CROB), Rionero in Vulture, Italy.

Front Oncol ; 12: 824562, 2022.

Article en En | MEDLINE | ID: mdl-35371979

Palabras clave

acute myeloid leukemia; clonogenicity; differentiation; extracellular vesicles; hematopoiesis; hematopoietic stem progenitor cells; inflammatory cytokines; microRNAs

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