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An optimized platform for efficient siRNA delivery into human NK cells.
Palacios, Daniel; Momayyezi, Pouria; Huhn, Oisín; Ask, Eivind Heggernes; Dunst, Josefine; Malmberg, Karl-Johan; Hammer, Quirin.
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  • Palacios D; Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.
  • Momayyezi P; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Huhn O; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden.
  • Ask EH; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden.
  • Dunst J; Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.
  • Malmberg KJ; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Hammer Q; Division of Immunology and Allergy, Department of Medicine Solna, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden.
Eur J Immunol ; 52(7): 1190-1193, 2022 07.
Article en En | MEDLINE | ID: mdl-35416292
The molecular networks that regulate natural killer (NK) cell functions are not completely understood. Here, we present a workflow for efficient delivery of siRNA into human NK cells without compromising viability. This methodology represents a promising approach for rapidly interrogating gene functions in primary human NK cells.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Células Asesinas Naturales Idioma: En Revista: Eur J Immunol Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Células Asesinas Naturales Idioma: En Revista: Eur J Immunol Año: 2022 Tipo del documento: Article