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Engineered Cas12a-Plus nuclease enables gene editing with enhanced activity and specificity.
Huang, Hongxin; Huang, Guanjie; Tan, Zhihong; Hu, Yongfei; Shan, Lin; Zhou, Jiajian; Zhang, Xin; Ma, Shufeng; Lv, Weiqi; Huang, Tao; Liu, Yuchen; Wang, Dong; Zhao, Xiaoyang; Lin, Ying; Rong, Zhili.
Afiliación
  • Huang H; Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
  • Huang G; Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou, 510515, China.
  • Tan Z; Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou, 510515, China.
  • Hu Y; Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
  • Shan L; Department of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Zhou J; Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou, 510515, China.
  • Zhang X; Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
  • Ma S; Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou, 510515, China.
  • Lv W; Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou, 510515, China.
  • Huang T; Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
  • Liu Y; Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
  • Wang D; Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou, 510515, China.
  • Zhao X; Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou, 510515, China.
  • Lin Y; Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
  • Rong Z; Department of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
BMC Biol ; 20(1): 91, 2022 04 25.
Article en En | MEDLINE | ID: mdl-35468792
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Sistemas CRISPR-Cas / Edición Génica Idioma: En Revista: BMC Biol Asunto de la revista: BIOLOGIA Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Sistemas CRISPR-Cas / Edición Génica Idioma: En Revista: BMC Biol Asunto de la revista: BIOLOGIA Año: 2022 Tipo del documento: Article