Competing interactions give rise to two-state behavior and switch-like transitions in charge-rich intrinsically disordered proteins.

Zeng, Xiangze; Ruff, Kiersten M; Pappu, Rohit V

Zeng, Xiangze; Ruff, Kiersten M; Pappu, Rohit V.

Afiliación

Zeng X; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130.
Ruff KM; Center for Science & Engineering of Living Systems, Washington University in St. Louis, St. Louis, MO 63130.
Pappu RV; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130.

Proc Natl Acad Sci U S A ; 119(19): e2200559119, 2022 05 10.

Article en En | MEDLINE | ID: mdl-35512095

Asunto(s)

Proteínas Intrínsecamente Desordenadas; Simulación por Computador; Proteínas Intrínsecamente Desordenadas/química; Proteínas Intrínsecamente Desordenadas/genética; Conformación Proteica

Palabras clave

bistable; intrinsically disordered proteins; polyampholyte; polyzwitterion

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Intrínsecamente Desordenadas Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article

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