Synthesis of 3,4,5-trisubstituted isoxazoles in water via a [3 + 2]-cycloaddition of nitrile oxides and 1,3-diketones, ß-ketoesters, or ß-ketoamides.

Hossain, Md Imran; Khan, Md Imdadul H; Kim, Seong Jong; Le, Hoang V.

Afiliación

Hossain MI; Department of BioMolecular Sciences and Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, Mississippi 38677, USA.
Khan MIH; Department of BioMolecular Sciences and Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, Mississippi 38677, USA.
Kim SJ; Natural Products Utilization Research Unit, United States Department of Agriculture, Agricultural Research Service, University of Mississippi, Mississippi 38677, USA.
Le HV; Department of BioMolecular Sciences and Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, Mississippi 38677, USA.

Beilstein J Org Chem ; 18: 446-458, 2022.

Article en En | MEDLINE | ID: mdl-35529890