Models of enzyme inhibition and apparent dissociation constants from kinetic analysis to study the differential inhibition of aldose reductase.

Balestri, Francesco; Cappiello, Mario; Moschini, Roberta; Mura, Umberto; Del-Corso, Antonella

Balestri, Francesco; Cappiello, Mario; Moschini, Roberta; Mura, Umberto; Del-Corso, Antonella.

Afiliación

Balestri F; Department of Biology, Biochemistry Unit, University of Pisa, Pisa, Italy.
Cappiello M; Department of Biology, Biochemistry Unit, University of Pisa, Pisa, Italy.
Moschini R; Department of Biology, Biochemistry Unit, University of Pisa, Pisa, Italy.
Mura U; Department of Biology, Biochemistry Unit, University of Pisa, Pisa, Italy.
Del-Corso A; Department of Biology, Biochemistry Unit, University of Pisa, Pisa, Italy.

J Enzyme Inhib Med Chem ; 37(1): 1426-1436, 2022 Dec.

Article en En | MEDLINE | ID: mdl-35607924

Asunto(s)

Aldehído Reductasa; Inhibidores Enzimáticos; Inhibidores Enzimáticos/farmacología; Cinética

Palabras clave

AKR1B1; Enzyme inhibition; aldose reductase; apparent kinetic constants; incomplete inhibition

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Aldehído Reductasa / Inhibidores Enzimáticos Idioma: En Revista: J Enzyme Inhib Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2022 Tipo del documento: Article

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