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Targeting PARP11 to avert immunosuppression and improve CAR T therapy in solid tumors.
Zhang, Hongru; Yu, Pengfei; Tomar, Vivek S; Chen, Xiangjie; Atherton, Matthew J; Lu, Zhen; Zhang, Hong-Guang; Li, Shifeng; Ortiz, Angelica; Gui, Jun; Leu, N Adrian; Yan, Fangxue; Blanco, Andres; Meyer-Ficca, Mirella L; Meyer, Ralph G; Beiting, Daniel P; Li, Jinyang; Nunez-Cruz, Selene; O'Connor, Roddy S; Johnson, Lexus R; Minn, Andy J; George, Subin S; Koumenis, Constantinos; Diehl, J Alan; Milone, Michael C; Zheng, Hui; Fuchs, Serge Y.
Afiliación
  • Zhang H; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Yu P; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Tomar VS; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Chen X; Institutes of Biology and Medical Sciences and Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China.
  • Atherton MJ; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Lu Z; Department of Clinical Sciences & Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Zhang HG; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Li S; Institutes of Biology and Medical Sciences and Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China.
  • Ortiz A; Dept. of Intensive Care Medicine, First Affiliated Hospital of Soochow University, Suzhou, China.
  • Gui J; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Leu NA; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Yan F; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Blanco A; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Meyer-Ficca ML; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Meyer RG; Department of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences and School of Veterinary Medicine, Utah State University, Logan, UT, USA.
  • Beiting DP; Department of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences and School of Veterinary Medicine, Utah State University, Logan, UT, USA.
  • Li J; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Nunez-Cruz S; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • O'Connor RS; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Johnson LR; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Minn AJ; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • George SS; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Koumenis C; Mark Foundation Center for Immunotherapy, Immune Signaling, and Radiation, University of Pennsylvania, Philadelphia, PA, USA.
  • Diehl JA; Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Milone MC; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Zheng H; Department of Biochemistry, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, USA.
  • Fuchs SY; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Nat Cancer ; 3(7): 808-820, 2022 07.
Article en En | MEDLINE | ID: mdl-35637402
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Poli(ADP-Ribosa) Polimerasas / Receptores Quiméricos de Antígenos / Neoplasias Idioma: En Revista: Nat Cancer Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Poli(ADP-Ribosa) Polimerasas / Receptores Quiméricos de Antígenos / Neoplasias Idioma: En Revista: Nat Cancer Año: 2022 Tipo del documento: Article