CT-001 is a rapid clearing factor VIIa with enhanced clearance and hemostatic activity for the treatment of acute bleeding in non-hemophilia settings.

Sim, Derek S; Mallari, Cornell R; Teare, John M; Bauzon, Maxine; Hermiston, Terry W

Sim, Derek S; Mallari, Cornell R; Teare, John M; Bauzon, Maxine; Hermiston, Terry W.

Afiliación

Sim DS; Coagulant Therapeutics Corporation, Berkeley, CA 94720, United States of America. Electronic address: dsim@coagulanttherapeutics.com.
Mallari CR; Coagulant Therapeutics Corporation, Berkeley, CA 94720, United States of America.
Teare JM; Coagulant Therapeutics Corporation, Berkeley, CA 94720, United States of America.
Bauzon M; Bayer HealthCare, San Francisco, CA 94258, United States of America.
Hermiston TW; Coagulant Therapeutics Corporation, Berkeley, CA 94720, United States of America.

Thromb Res ; 215: 58-66, 2022 07.

Article en En | MEDLINE | ID: mdl-35640516

Asunto(s)

Factor VIIa; Hemostáticos; Animales; Modelos Animales de Enfermedad; Factor VIIa/farmacología; Factor VIIa/uso terapéutico; Hemorragia/tratamiento farmacológico; Humanos; Ratones; Tromboplastina; Tomografía Computarizada por Rayos X

Palabras clave

Asialoglycoprotein receptor; Blood coagulation; Factor VIIa; Haemostasis; Hemorrhage; Protein engineering

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Hemostáticos / Factor VIIa Tipo de estudio: Prognostic_studies Idioma: En Revista: Thromb Res Año: 2022 Tipo del documento: Article

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