Pinnae and facial hypertrichosis induced by cetuximab.
J Oncol Pharm Pract
; 29(3): 731-737, 2023 Apr.
Article
en En
| MEDLINE
| ID: mdl-35821579
ABSTRACT
INTRODUCTION:
Anti-EGFR targeted anti-cancer treatment is associated with various skin adverse events. Cetuximab is often associated with acneiform papules and skin disorders. Hypertrichosis cited in face pinnae and eyelash trichomegaly are seldom described. CASE REPORT A 72-year-old female cancer patient presented deteriorating facial-pinnae hypertrichosis and eyelash prolongation post cetuximab infusion. MANAGEMENT ANDOUTCOME:
Consecutive cetuximab administration led to exaggerating hairy skin side effects, fully alleviated when the drug was discontinued.DISCUSSION:
To the best of our knowledge, this is the first reported case of an anti-EGFR-associated diffuse pinnae hypertrichosis presentation in a female patient in literature. This distinct entity can be easily diagnosed and manipulated with early drug withdrawal. An extensive review of relevant basic molecular research is provided to increase physicians' awareness.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Enfermedades de la Piel
/
Hipertricosis
/
Antineoplásicos
Idioma:
En
Revista:
J Oncol Pharm Pract
Asunto de la revista:
FARMACIA
Año:
2023
Tipo del documento:
Article