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Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells.
Mehta, Stuti; Buyanbat, Altantsetseg; Kai, Yan; Karayel, Ozge; Goldman, Seth Raphael; Seruggia, Davide; Zhang, Kevin; Fujiwara, Yuko; Donovan, Katherine A; Zhu, Qian; Yang, Huan; Nabet, Behnam; Gray, Nathanael S; Mann, Matthias; Fischer, Eric S; Adelman, Karen; Orkin, Stuart H.
Afiliación
  • Mehta S; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA 02115, USA.
  • Buyanbat A; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA 02115, USA.
  • Kai Y; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA 02115, USA.
  • Karayel O; Department of Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, 82152 Planegg, Germany.
  • Goldman SR; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Seruggia D; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
  • Zhang K; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA 02115, USA.
  • Fujiwara Y; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA 02115, USA.
  • Donovan KA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Zhu Q; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA 02115, USA.
  • Yang H; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA 02115, USA.
  • Nabet B; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
  • Gray NS; Department of Chemical and Systems Biology, CHEM-H and SCI, Stanford Medical School, Stanford University, Stanford, CA, USA.
  • Mann M; Department of Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, 82152 Planegg, Germany.
  • Fischer ES; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Adelman K; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Orkin SH; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA 02115, USA; Howard Hughes Medical Institute and Harvard Medical School, Boston, MA 02115, USA. Electronic address: stuart_orkin@dfci.harvard.edu.
Cell Chem Biol ; 29(8): 1273-1287.e8, 2022 08 18.
Article en En | MEDLINE | ID: mdl-35839780
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Nucleares / Proteoma Idioma: En Revista: Cell Chem Biol Año: 2022 Tipo del documento: Article
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Nucleares / Proteoma Idioma: En Revista: Cell Chem Biol Año: 2022 Tipo del documento: Article