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Abusive head injury in the very young: outcomes from a Singapore children's hospital.
Primalani, Nishal Kishinchand; Chan, Yiong Huak; Ng, Zhi Min; Chong, Shu-Ling; Seow, Wan Tew; Loh, Lik Eng; Mok, Yee Hui; Low, Sharon Y Y.
Afiliación
  • Primalani NK; Neurosurgical Service, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, 229899, Singapore.
  • Chan YH; Biostatistics Unit, Yong Loo Lin School of Medicine, National University of Singapore, Block MD11, Clinical Research Centre, #02-03 (c/o CBmE Office), 10 Medical Drive, Singapore, 117597, Singapore.
  • Ng ZM; Neurology Service, Department of Paediatrics, KK Women's and Children's Hospital, Singapore, Singapore.
  • Chong SL; Children's Emergency, KK Women's and Children's Hospital, Singapore, Singapore.
  • Seow WT; Neurosurgical Service, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, 229899, Singapore.
  • Loh LE; Department of Neurosurgery, National Neuroscience Institute, Singapore, Singapore.
  • Mok YH; SingHealth Duke-NUS Neuroscience Academic Clinical Program, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.
  • Low SYY; Children's Intensive Care Unit, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, 229899, Singapore.
Childs Nerv Syst ; 38(12): 2397-2407, 2022 12.
Article en En | MEDLINE | ID: mdl-35851614
ABSTRACT

PURPOSE:

Abusive head trauma (AHT) is a serious problem in children. The aims of this study are to identify risk factors that correlate with outcomes for those requiring neurosurgical intervention for very young children with AHT, assessment of variables associated with outcomes, and corroboration of our results with literature.

METHODS:

This is an ethics-approved, retrospective study. Inclusion criteria consisted of patients aged 2 years old or less with a diagnosis of AHT managed by the Neurosurgical Service, KK Women's and Children's Hospital. Demographical and clinical variables are incorporated in the statistical analyses. Logistic regression was applied to statistically significant variables for the risk prediction model.

RESULTS:

From 2000 to 2020, 24 patients required surgery for AHT. Timepoint was set at 12 months post-diagnosis. Univariate analyses demonstrated that patients with mild TBI were likely to have a favourable GOS-E Peds (p = 0.01), whereas radiological presence of cerebral oedema (p < .001), development of scar epilepsy (p = 0.021), and progression to cerebral palsy (p = 0.001) were associated with unfavourable GOS-E Peds.

CONCLUSION:

This is the first study focused on neurosurgical outcomes for very young children with AHT in Singapore. We advocate multidisciplinary efforts to improve outcomes for this devastating condition.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Maltrato a los Niños / Traumatismos Craneocerebrales Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies País/Región como asunto: Asia Idioma: En Revista: Childs Nerv Syst Asunto de la revista: NEUROLOGIA / PEDIATRIA Año: 2022 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Maltrato a los Niños / Traumatismos Craneocerebrales Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies País/Región como asunto: Asia Idioma: En Revista: Childs Nerv Syst Asunto de la revista: NEUROLOGIA / PEDIATRIA Año: 2022 Tipo del documento: Article