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Evolution and Transmission of Cefiderocol-Resistant Acinetobacter baumannii During an Outbreak in the Burn Intensive Care Unit.
Smoke, Steven M; Brophy, Alison; Reveron, Samuel; Iovleva, Alina; Kline, Ellen G; Marano, Michael; Miller, Lincoln P; Shields, Ryan K.
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  • Smoke SM; Department of Pharmacy, Cooperman Barnabas Medical Center, Livingston, New Jersey, USA.
  • Brophy A; Department of Pharmacy, Cooperman Barnabas Medical Center, Livingston, New Jersey, USA.
  • Reveron S; Department of Pharmacy, Cooperman Barnabas Medical Center, Livingston, New Jersey, USA.
  • Iovleva A; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Kline EG; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Marano M; Department of Surgery, Cooperman Barnabas Medical Center, Livingston, New Jersey, USA.
  • Miller LP; Department of Medicine, Cooperman Barnabas Medical Center, Livingston, New Jersey, USA.
  • Shields RK; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Clin Infect Dis ; 76(3): e1261-e1265, 2023 02 08.
Article en En | MEDLINE | ID: mdl-35974429
We report on 11 critically ill burn patients treated with cefiderocol for carbapenem-resistant Acinetobacter baumannii infections. Clinical success was achieved in 36% and complicated by treatment-emergent resistance and interpatient transmission of cefiderocol-resistant A. baumannii. Resistant isolates harbored disrupted pirA and piuA genes that were not disrupted among susceptible isolates.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Infecciones por Acinetobacter / Acinetobacter baumannii Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Infecciones por Acinetobacter / Acinetobacter baumannii Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2023 Tipo del documento: Article