Combination of the lateral-flow immunoassay with multicolor gold nanorod etching for the semi-quantitative detection of digoxin.

Bradbury, Daniel W; Trinh, Jasmine T; Ryan, Milo J; Chen, Kyle J; Battikha, Adel A; Wu, Benjamin M; Kamei, Daniel T

Bradbury, Daniel W; Trinh, Jasmine T; Ryan, Milo J; Chen, Kyle J; Battikha, Adel A; Wu, Benjamin M; Kamei, Daniel T.

Afiliación

Bradbury DW; Department of Bioengineering, University of California, Los Angeles, CA 90095, USA. kamei@seas.ucla.edu.
Trinh JT; Department of Bioengineering, University of California, Los Angeles, CA 90095, USA. kamei@seas.ucla.edu.
Ryan MJ; Department of Bioengineering, University of California, Los Angeles, CA 90095, USA. kamei@seas.ucla.edu.
Chen KJ; Department of Bioengineering, University of California, Los Angeles, CA 90095, USA. kamei@seas.ucla.edu.
Battikha AA; Department of Bioengineering, University of California, Los Angeles, CA 90095, USA. kamei@seas.ucla.edu.
Wu BM; Department of Bioengineering, University of California, Los Angeles, CA 90095, USA. kamei@seas.ucla.edu.
Kamei DT; Division of Advanced Prosthodontics & Weintraub Center for Reconstructive Biotechnology, School of Dentistry, University of California, Los Angeles, CA 90095, USA.

Analyst ; 147(18): 4000-4007, 2022 Sep 12.

Article en En | MEDLINE | ID: mdl-35993251

ABSTRACT

ABSTRACT

We are the first to combine the lateral-flow immunoassay (LFA) with gold nanorod (GNR) etching to achieve a multicolor readout where the color produced was correlated with digoxin concentrations in human serum in the relevant range for therapeutic drug monitoring of 0.5-3.0 ng mL-1.

Asunto(s)

Oro; Nanotubos; Digoxina; Humanos; Inmunoensayo; Límite de Detección

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Nanotubos / Oro Tipo de estudio: Diagnostic_studies Idioma: En Revista: Analyst Año: 2022 Tipo del documento: Article

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