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Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism.
Yoshida, Yohko; Shimizu, Ippei; Shimada, Atsuhiro; Nakahara, Keita; Yanagisawa, Sachiko; Kubo, Minoru; Fukuda, Shinji; Ishii, Chiharu; Yamamoto, Hiromitsu; Ishikawa, Takamasa; Kano, Kuniyuki; Aoki, Junken; Katsuumi, Goro; Suda, Masayoshi; Ozaki, Kazuyuki; Yoshida, Yutaka; Okuda, Shujiro; Ohta, Shigeo; Okamoto, Shiki; Minokoshi, Yasuhiko; Oda, Kanako; Sasaoka, Toshikuni; Abe, Manabu; Sakimura, Kenji; Kubota, Yoshiaki; Yoshimura, Norihiko; Kajimura, Shingo; Zuriaga, Maria; Walsh, Kenneth; Soga, Tomoyoshi; Minamino, Tohru.
Afiliación
  • Yoshida Y; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, 113-8431, Japan.
  • Shimizu I; Department of Advanced Senotherapeutics, Juntendo University Graduate School of Medicine, Tokyo, 113-8431, Japan.
  • Shimada A; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, 113-8431, Japan. s.shimizu@juntendo.ac.jp.
  • Nakahara K; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan. s.shimizu@juntendo.ac.jp.
  • Yanagisawa S; Department of Applied Life Science, Faculty of Applied Biological Sciences, Gifu University, Gifu, 501-1193, Japan.
  • Kubo M; Department of Applied Life Science, Faculty of Applied Biological Sciences, Gifu University, Gifu, 501-1193, Japan.
  • Fukuda S; Graduate School of Science, University of Hyogo, Hyogo, 678-1297, Japan.
  • Ishii C; Graduate School of Science, University of Hyogo, Hyogo, 678-1297, Japan.
  • Yamamoto H; Institute for Advanced Biosciences, Keio University, 246-2 Mizukami, Kakuganji, Tsuruoka, Yamagata, 997-0052, Japan.
  • Ishikawa T; Intestinal Microbiota Project, Kanagawa Institute of Industrial Science and Technology, Kanagawa, 210-0821, Japan.
  • Kano K; Transborder Medical Research Center, University of Tsukuba, Ibaraki, 305-8575, Japan.
  • Aoki J; Institute for Advanced Biosciences, Keio University, 246-2 Mizukami, Kakuganji, Tsuruoka, Yamagata, 997-0052, Japan.
  • Katsuumi G; Institute for Advanced Biosciences, Keio University, 246-2 Mizukami, Kakuganji, Tsuruoka, Yamagata, 997-0052, Japan.
  • Suda M; Institute for Advanced Biosciences, Keio University, 246-2 Mizukami, Kakuganji, Tsuruoka, Yamagata, 997-0052, Japan.
  • Ozaki K; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, 113-0033, Japan.
  • Yoshida Y; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, 113-0033, Japan.
  • Okuda S; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, 113-8431, Japan.
  • Ohta S; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, 113-8431, Japan.
  • Okamoto S; Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, 951-8510, Japan.
  • Minokoshi Y; Department of Structural Pathology, Kidney Research Center, Niigata University Graduate School of Medical and Dental Sciences, Niigata, 951-8510, Japan.
  • Oda K; Division of Bioinformatics, Niigata University Graduate School of Medical and Dental Sciences, Niigata, 951-8510, Japan.
  • Sasaoka T; Department of Neurology, Juntendo University Graduate School of Medicine, Tokyo, 113-8421, Japan.
  • Abe M; Second Department of Internal Medicine (Endocrinology, Diabetes and Metabolism, Hematology, Rheumatology), Graduate School of Medicine, University of the Ryukyus, Okinawa, 903-0215, Japan.
  • Sakimura K; Department of Homeostatic Regulation, Division of Endocrinology and Metabolism, National Institutes of Natural Sciences, National Institute for Physiological Sciences, Aichi, 444-8585, Japan.
  • Kubota Y; Department of Comparative and Experimental Medicine, Brain Research Institute, Niigata University, Niigata, 951-8585, Japan.
  • Yoshimura N; Department of Comparative and Experimental Medicine, Brain Research Institute, Niigata University, Niigata, 951-8585, Japan.
  • Kajimura S; Department of Cellular Neurobiology, Brain Research Institute, Niigata University, Niigata, 951-8585, Japan.
  • Zuriaga M; Department of Animal Model Development, Brain Research Institute, Niigata University, Niigata, 951-8585, Japan.
  • Walsh K; Department of Cellular Neurobiology, Brain Research Institute, Niigata University, Niigata, 951-8585, Japan.
  • Soga T; Department of Animal Model Development, Brain Research Institute, Niigata University, Niigata, 951-8585, Japan.
  • Minamino T; Department of Anatomy, Keio University School of Medicine, Tokyo, 160-8582, Japan.
Sci Rep ; 12(1): 14883, 2022 09 01.
Article en En | MEDLINE | ID: mdl-36050466
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Insuficiencia Cardíaca / Infarto del Miocardio Tipo de estudio: Prognostic_studies Idioma: En Revista: Sci Rep Año: 2022 Tipo del documento: Article
Texto completo
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XML
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Insuficiencia Cardíaca / Infarto del Miocardio Tipo de estudio: Prognostic_studies Idioma: En Revista: Sci Rep Año: 2022 Tipo del documento: Article