Sialic Acid 4-N-Piperazine and Piperidine Derivatives Bind with High Affinity to the P. mirabilis Sialic Acid Sodium Solute Symporter.

Bozzola, Tiago; Johnsson, Richard E; Nilsson, Ulf J; Ellervik, Ulf

Bozzola, Tiago; Johnsson, Richard E; Nilsson, Ulf J; Ellervik, Ulf.

Afiliación

Bozzola T; Department of Chemistry, Lund University, P.O. Box 124, 221 00, Lund, Sweden.
Johnsson RE; Red Glead Discovery AB, Medicon Village, 22381, Lund, Sweden.
Nilsson UJ; Department of Chemistry, Lund University, P.O. Box 124, 221 00, Lund, Sweden.
Ellervik U; Department of Chemistry, Lund University, P.O. Box 124, 221 00, Lund, Sweden.

ChemMedChem ; 17(23): e202200351, 2022 12 05.

Article en En | MEDLINE | ID: mdl-36121381

Asunto(s)

Simportadores; Piperazina; Sodio; Ácido N-Acetilneuramínico

Palabras clave

Antibacterial agents; Proteus mirabilis; Sialic acid; Stereoselective amination; Uptake inhibition

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Simportadores Idioma: En Revista: ChemMedChem Asunto de la revista: FARMACOLOGIA / QUIMICA Año: 2022 Tipo del documento: Article

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