Bisdemethoxycurcumin suppresses human osteosarcoma U­2 OS cell migration and invasion via affecting the PI3K/Akt/NF­&#954;B, PI3K/Akt/GSK3ß and MAPK signaling pathways <i>in vitro</i>.

Ma, Yi-Shih; Peng, Shu-Fen; Wu, Rick Sai-Chuen; Chueh, Fu-Shin; Huang, Wen-Wen; Chen, Po-Yuan; Kuo, Chao-Lin; Huang, An-Cheng; Liao, Ching-Lung; Hsia, Te-Chun

Bisdemethoxycurcumin suppresses human osteosarcoma U2 OS cell migration and invasion via affecting the PI3K/Akt/NFκB, PI3K/Akt/GSK3ß and MAPK signaling pathways in vitro.

Ma, Yi-Shih; Peng, Shu-Fen; Wu, Rick Sai-Chuen; Chueh, Fu-Shin; Huang, Wen-Wen; Chen, Po-Yuan; Kuo, Chao-Lin; Huang, An-Cheng; Liao, Ching-Lung; Hsia, Te-Chun.

Afiliación

Ma YS; School of Chinese Medicine for PostBaccalaureate, College of Medicine, IShou University, Kaohsiung 82445, Taiwan, R.O.C.
Peng SF; Department of Biological Science and Technology, China Medical University, Taichung 406040, Taiwan, R.O.C.
Wu RS; Department of Anesthesiology, China Medical University Hospital, Taichung 404332, Taiwan, R.O.C.
Chueh FS; Department of Food Nutrition and Health Biotechnology, Asia University, Taichung 413305, Taiwan, R.O.C.
Huang WW; Department of Biological Science and Technology, China Medical University, Taichung 406040, Taiwan, R.O.C.
Chen PY; Department of Biological Science and Technology, China Medical University, Taichung 406040, Taiwan, R.O.C.
Kuo CL; Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung 406040, Taiwan, R.O.C.
Huang AC; Department of Nursing, St. Mary's Junior College of Medicine, Nursing and Management, Yilan 26647, Taiwan, R.O.C.
Liao CL; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung 406040, Taiwan, R.O.C.
Hsia TC; Department of Respiratory Therapy, China Medical University, Taichung 404333, Taiwan, R.O.C.

Oncol Rep ; 48(6)2022 12.

Article en En | MEDLINE | ID: mdl-36222295

Asunto(s)

Productos Biológicos; Neoplasias Óseas; Osteosarcoma; Productos Biológicos/farmacología; Neoplasias Óseas/patología; Cadherinas; Línea Celular Tumoral; Movimiento Celular; Proliferación Celular; Diarilheptanoides; Gelatina/farmacología; Gelatina/uso terapéutico; Glucógeno Sintasa Quinasa 3 beta/metabolismo; Humanos; Metaloproteinasa 13 de la Matriz/metabolismo; Metaloproteinasa 2 de la Matriz/metabolismo; Metaloproteinasa 9 de la Matriz/metabolismo; FN-kappa B/metabolismo; Invasividad Neoplásica; Osteosarcoma/patología; Fosfatidilinositol 3-Quinasas/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; Calidad de Vida; Transducción de Señal; Vimentina/metabolismo

Palabras clave

MAPK; PI3K/Akt/GSK3ß; PI3K/Akt/NFκB; bisdemethoxycurcumin; cell migration and invasion; human osteosarcoma cells

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Productos Biológicos / Neoplasias Óseas / Osteosarcoma Idioma: En Revista: Oncol Rep Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article

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