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Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression.
Li, Zhongchi; Low, Vivien; Luga, Valbona; Sun, Janet; Earlie, Ethan; Parang, Bobak; Shobana Ganesh, Kripa; Cho, Sungyun; Endress, Jennifer; Schild, Tanya; Hu, Mengying; Lyden, David; Jin, Wenbing; Guo, Chunjun; Dephoure, Noah; Cantley, Lewis C; Laughney, Ashley M; Blenis, John.
Afiliación
  • Li Z; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, 10021, USA.
  • Low V; Department of Pharmacology, Weill Cornell Medicine, New York, NY, 10021, USA.
  • Luga V; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, 10021, USA.
  • Sun J; Department of Pharmacology, Weill Cornell Medicine, New York, NY, 10021, USA.
  • Earlie E; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, 10021, USA.
  • Parang B; Department of Medicine, Weill Cornell Medicine, New York, NY, 10021, USA.
  • Shobana Ganesh K; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, 10021, USA.
  • Cho S; Department of Medicine, Weill Cornell Medicine, New York, NY, 10021, USA.
  • Endress J; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, 10021, USA.
  • Schild T; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.
  • Hu M; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, 10021, USA.
  • Lyden D; Department of Pharmacology, Weill Cornell Medicine, New York, NY, 10021, USA.
  • Jin W; Department of Medicine, Weill Cornell Medicine, New York, NY, 10021, USA.
  • Guo C; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, 10021, USA.
  • Dephoure N; Department of Biochemistry, Weill Cornell Medicine, New York, NY, 10021, USA.
  • Cantley LC; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, 10021, USA.
  • Laughney AM; Department of Pharmacology, Weill Cornell Medicine, New York, NY, 10021, USA.
  • Blenis J; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, 10021, USA.
Nat Commun ; 13(1): 6239, 2022 10 20.
Article en En | MEDLINE | ID: mdl-36266345
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Vesículas Extracelulares / Fibroblastos Asociados al Cáncer / Neoplasias Tipo de estudio: Risk_factors_studies Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Vesículas Extracelulares / Fibroblastos Asociados al Cáncer / Neoplasias Tipo de estudio: Risk_factors_studies Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article