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Maternal and neonatal outcomes in pregnancies with type 2 diabetes in First Nation and other Manitoban people: a population-based study.
Yamamoto, Jennifer M; Pylypjuk, Christy; Sellers, Elizabeth; McLeod, Lorraine; Wicklow, Brandy; Sirski, Monica; Prior, Heather; Ruth, Chelsea.
Afiliación
  • Yamamoto JM; Department of Internal Medicine (Yamamoto), University of Manitoba; Children's Hospital Research Institute of Manitoba (Yamamoto, Pylypjuk, Sellers, Wicklow); Departments of Obstetrics, Gynecology and Reproductive Sciences (Pylypjuk), and Pediatrics and Child Health (Sellers, Wicklow, Ruth), Univers
  • Pylypjuk C; Department of Internal Medicine (Yamamoto), University of Manitoba; Children's Hospital Research Institute of Manitoba (Yamamoto, Pylypjuk, Sellers, Wicklow); Departments of Obstetrics, Gynecology and Reproductive Sciences (Pylypjuk), and Pediatrics and Child Health (Sellers, Wicklow, Ruth), Univers
  • Sellers E; Department of Internal Medicine (Yamamoto), University of Manitoba; Children's Hospital Research Institute of Manitoba (Yamamoto, Pylypjuk, Sellers, Wicklow); Departments of Obstetrics, Gynecology and Reproductive Sciences (Pylypjuk), and Pediatrics and Child Health (Sellers, Wicklow, Ruth), Univers
  • McLeod L; Department of Internal Medicine (Yamamoto), University of Manitoba; Children's Hospital Research Institute of Manitoba (Yamamoto, Pylypjuk, Sellers, Wicklow); Departments of Obstetrics, Gynecology and Reproductive Sciences (Pylypjuk), and Pediatrics and Child Health (Sellers, Wicklow, Ruth), Univers
  • Wicklow B; Department of Internal Medicine (Yamamoto), University of Manitoba; Children's Hospital Research Institute of Manitoba (Yamamoto, Pylypjuk, Sellers, Wicklow); Departments of Obstetrics, Gynecology and Reproductive Sciences (Pylypjuk), and Pediatrics and Child Health (Sellers, Wicklow, Ruth), Univers
  • Sirski M; Department of Internal Medicine (Yamamoto), University of Manitoba; Children's Hospital Research Institute of Manitoba (Yamamoto, Pylypjuk, Sellers, Wicklow); Departments of Obstetrics, Gynecology and Reproductive Sciences (Pylypjuk), and Pediatrics and Child Health (Sellers, Wicklow, Ruth), Univers
  • Prior H; Department of Internal Medicine (Yamamoto), University of Manitoba; Children's Hospital Research Institute of Manitoba (Yamamoto, Pylypjuk, Sellers, Wicklow); Departments of Obstetrics, Gynecology and Reproductive Sciences (Pylypjuk), and Pediatrics and Child Health (Sellers, Wicklow, Ruth), Univers
  • Ruth C; Department of Internal Medicine (Yamamoto), University of Manitoba; Children's Hospital Research Institute of Manitoba (Yamamoto, Pylypjuk, Sellers, Wicklow); Departments of Obstetrics, Gynecology and Reproductive Sciences (Pylypjuk), and Pediatrics and Child Health (Sellers, Wicklow, Ruth), Univers
CMAJ Open ; 10(4): E930-E936, 2022.
Article en En | MEDLINE | ID: mdl-36280248
ABSTRACT

BACKGROUND:

First Nation people living in Canada experience a high prevalence of type 2 diabetes in pregnancy. In this study, we aimed to describe maternal and neonatal outcomes in First Nation and all other females with type 2 diabetes living in Manitoba, Canada.

METHODS:

This was a population-level retrospective cohort study using linked administrative data from Manitoba (2012-2017). We compared First Nation females with type 2 diabetes with all other Manitoban females with type 2 diabetes, using relative risks (RRs) and 95% confidence intervals (CIs).

RESULTS:

A total of 2181 females with type 2 diabetes were included, and 1218 (55.8%) were First Nation. First Nation females with type 2 diabetes were significantly more likely to experience stillbirth (RR 2.14, 95% CI 1.11-4.13) and perinatal death (RR 2.39, 95% CI 1.37-4.17) than all other Manitoban females with type 2 diabetes. Offspring of First Nation females with type 2 diabetes had a higher risk of most neonatal complications than offspring of all other Manitoban females with type 2 diabetes, including a higher risk of congenital malformations (RR 1.97, 95% CI 1.30-2.99), but First Nation people did not have a higher risk of most maternal complications.

INTERPRETATION:

First Nation pregnant individuals living with type 2 diabetes experienced a higher risk for adverse pregnancy outcomes than all other Manitoban females with type 2 diabetes. Additional studies are needed to identify both high-risk and protective factors for pregnancy complications in First Nation people living with type 2 diabetes in pregnancy.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Complicaciones del Embarazo / Diabetes Mellitus Tipo 2 Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: CMAJ Open Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Complicaciones del Embarazo / Diabetes Mellitus Tipo 2 Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: CMAJ Open Año: 2022 Tipo del documento: Article