Evaluation of aversive behavior in Rattus norvegicus experimentally infected by two distinct strains of Toxoplasma gondii (ME49 and VEG): study of epigenetic markers.
Rev Soc Bras Med Trop
; 55: e01222022, 2022.
Article
en En
| MEDLINE
| ID: mdl-36287471
ABSTRACT
BACKGROUND:
Behavioral changes in Rattus norvegicus infected with two strains of Toxoplasma gondii (ME49 and VEG) were investigated.METHODS:
Rats were evaluated for motor activity and aversion or attraction to cat urine 60 days after infection. After euthanasia, arginine-vasopressin gene methylation in the central nervous system was evaluated.RESULTS:
A significant difference was observed in the methylation of the arginine-vasopressin promoter gene between rats infected with the ME49 and VEG strains.CONCLUSIONS:
Although differences were not observed in many parameters, significant differences were observed in the methylation of the arginine-vasopressin promoter gene in rats infected with the two studied strains.
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Base de datos:
MEDLINE
Asunto principal:
Toxoplasma
/
Toxoplasmosis Animal
Idioma:
En
Revista:
Rev Soc Bras Med Trop
Año:
2022
Tipo del documento:
Article