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BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling.
Shaashua, Lee; Ben-Shmuel, Aviad; Pevsner-Fischer, Meirav; Friedman, Gil; Levi-Galibov, Oshrat; Nandakumar, Subhiksha; Barki, Debra; Nevo, Reinat; Brown, Lauren E; Zhang, Wenhan; Stein, Yaniv; Lior, Chen; Kim, Han Sang; Bojmar, Linda; Jarnagin, William R; Lecomte, Nicolas; Mayer, Shimrit; Stok, Roni; Bishara, Hend; Hamodi, Rawand; Levy-Lahad, Ephrat; Golan, Talia; Porco, John A; Iacobuzio-Donahue, Christine A; Schultz, Nikolaus; Tuveson, David A; Lyden, David; Kelsen, David; Scherz-Shouval, Ruth.
Afiliación
  • Shaashua L; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.
  • Ben-Shmuel A; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.
  • Pevsner-Fischer M; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.
  • Friedman G; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.
  • Levi-Galibov O; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.
  • Nandakumar S; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Barki D; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.
  • Nevo R; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.
  • Brown LE; Department of Chemistry and Center for Molecular Discovery (BU-CMD), Boston University, Boston, MA, USA.
  • Zhang W; Department of Chemistry and Center for Molecular Discovery (BU-CMD), Boston University, Boston, MA, USA.
  • Stein Y; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.
  • Lior C; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.
  • Kim HS; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Bojmar L; Yonsei Cancer Center, Division of Medical Oncology, Department of Internal Medicine, Graduate School of Medical Science, Brain Korea 21 Project, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.
  • Jarnagin WR; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Lecomte N; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
  • Mayer S; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Stok R; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Bishara H; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.
  • Hamodi R; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.
  • Levy-Lahad E; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.
  • Golan T; Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.
  • Porco JA; The Fuld Family Medical Genetics Institute, Shaare Zedek Medical Center, Jerusalem, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
  • Iacobuzio-Donahue CA; Oncology Institute, Sheba Medical Center at Tel-Hashomer, Tel Aviv University, Tel Aviv, Israel.
  • Schultz N; Department of Chemistry and Center for Molecular Discovery (BU-CMD), Boston University, Boston, MA, USA.
  • Tuveson DA; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Lyden D; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Kelsen D; Cancer Center, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.
  • Scherz-Shouval R; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
Nat Commun ; 13(1): 6513, 2022 10 31.
Article en En | MEDLINE | ID: mdl-36316305
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático / Clusterina / Fibroblastos Asociados al Cáncer / Factores de Transcripción del Choque Térmico Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático / Clusterina / Fibroblastos Asociados al Cáncer / Factores de Transcripción del Choque Térmico Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article