Detection and genetic characterization of canine distemper virus isolated in civets in Vietnam.
Res Vet Sci
; 154: 97-101, 2023 Jan.
Article
en En
| MEDLINE
| ID: mdl-36521201
ABSTRACT
Canine distemper (CD), caused by the canine distemper virus (CDV), is a lethal systemic disease to a wide range of wild and domestic carnivorous hosts, including civets. In this study, a possible CD outbreak in a backyard farm with 32 diseased civets (Viverricula indica) in Hanoi, Vietnam, was investigated. The sick civets showed CD-like clinical signs such as anorexia, sedentary behavior, diarrhea, dermatitis, nasal, and footpad hyperkeratosis. Various tissue samples collected from the dead civets were utilized for molecular screening of CDV and histopathological examination. The genetic detection and characterization confirmed that samples collected from dead civets tested positive for CDV. The phylogenetic analysis based on the full-length H gene sequences indicated that all CDV strains isolated from civets belonged to the Asia-1 lineage and were closely related to the CDV strains previously reported from dogs in Thailand, China, and Vietnam. Histopathological examination showed severe interstitial pneumonia, hemorrhagic alveolar septa, necrotic alveolar epithelial cells, necrotic, degenerated, or lost Purkinje cells, eosinophilic intracytoplasmic inclusion bodies, edema, and perivascular cuff. This study confirmed the detection of CDV in civets for the first time in Vietnam.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Moquillo
/
Virus del Moquillo Canino
/
Enfermedades de los Perros
Tipo de estudio:
Diagnostic_studies
País/Región como asunto:
Asia
Idioma:
En
Revista:
Res Vet Sci
Año:
2023
Tipo del documento:
Article