Targeting the Autophagy-Lysosome Pathway in a Pathophysiologically Relevant Murine Model of Reversible Heart Failure.

Evans, Sarah; Ma, Xiucui; Wang, Xiqiang; Chen, Yana; Zhao, Chen; Weinheimer, Carla J; Kovacs, Attila; Finck, Brian; Diwan, Abhinav; Mann, Douglas L

Targeting the Autophagy-Lysosome Pathway in a Pathophysiologically Relevant Murine Model of Reversible Heart Failure.

Evans, Sarah; Ma, Xiucui; Wang, Xiqiang; Chen, Yana; Zhao, Chen; Weinheimer, Carla J; Kovacs, Attila; Finck, Brian; Diwan, Abhinav; Mann, Douglas L.

Afiliación

Evans S; Center for Cardiovascular Research, Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri, USA.
Ma X; Center for Cardiovascular Research, Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri, USA.
Wang X; Center for Cardiovascular Research, Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri, USA.
Chen Y; Division of Geriatrics & Nutritional Science, Washington University School of Medicine, St. Louis, Missouri, USA.
Zhao C; Center for Cardiovascular Research, Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri, USA.
Weinheimer CJ; Center for Cardiovascular Research, Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri, USA.
Kovacs A; Center for Cardiovascular Research, Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri, USA.
Finck B; Center for Cardiovascular Research, Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri, USA.
Diwan A; Division of Geriatrics & Nutritional Science, Washington University School of Medicine, St. Louis, Missouri, USA.
Mann DL; Center for Cardiovascular Research, Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri, USA.

JACC Basic Transl Sci ; 7(12): 1214-1228, 2022 Dec.

Article en En | MEDLINE | ID: mdl-36644282

Palabras clave

AAV9, adeno-associated virus 9; CMV, cytomegalovirus; CQ, chloroquine; GFP, green red fluorescent protein; HF, heart failure; HF-DB, TAC + MI mice that have undergone debanding; LFEF, left ventricular ejection fraction; LV, left ventricle; MI, myocardial infarction; RFP, red fluorescent protein; TAC, transaortic constriction; TEM, transmission electron microscopic; TFEB, transcription factor EB; autophagy; dsDNA, double stranded DNA; eGFP, enhanced green fluorescent protein; mTOR, mammalian target of rapamycin; reverse left ventricle remodeling

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Texto completo: 1 Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: JACC Basic Transl Sci Año: 2022 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: JACC Basic Transl Sci Año: 2022 Tipo del documento: Article