Thyroid hormone transporters binding affinity of methoxypoly chlorinated biphenyls: Insights from molecular simulations and fluorescence competitive binding experiment.

Jia, Dan; Miao, Wangli; Rui, Yuefan; Chen, Yanting; Liang, Wenhui; Yi, Zhongsheng

Jia, Dan; Miao, Wangli; Rui, Yuefan; Chen, Yanting; Liang, Wenhui; Yi, Zhongsheng.

Afiliación

Jia D; College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541004, China.
Miao W; College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541004, China.
Rui Y; College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541004, China.
Chen Y; College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541004, China.
Liang W; College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541004, China.
Yi Z; College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541004, China. Electronic address: yzs@glut.edu.cn.

Int J Biol Macromol ; 231: 123224, 2023 Mar 15.

Article en En | MEDLINE | ID: mdl-36649871

Asunto(s)

Bifenilos Policlorados; Recién Nacido; Humanos; Bifenilos Policlorados/metabolismo; Unión Competitiva; Prealbúmina; Hormonas Tiroideas/metabolismo; Tiroxina/metabolismo; Proteínas de Transporte de Membrana/metabolismo

Palabras clave

Binding free energy; Methoxylated polychlorinated biphenyl; Molecular docking; Molecular dynamic simulation

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Bifenilos Policlorados Idioma: En Revista: Int J Biol Macromol Año: 2023 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Bifenilos Policlorados Idioma: En Revista: Int J Biol Macromol Año: 2023 Tipo del documento: Article