Morphologic and Genetic Characterization of Ilheus Virus, a Potential Emergent Flavivirus in the Americas.
Viruses
; 15(1)2023 01 10.
Article
en En
| MEDLINE
| ID: mdl-36680235
ABSTRACT
Ilheus virus (ILHV) is a mosquito-borne flavivirus circulating throughout Central and South America and the Caribbean. It has been detected in several mosquito genera including Aedes and Culex, and birds are thought to be its primary amplifying and reservoir host. Here, we describe the genomic and morphologic characterization of ten ILHV strains. Our analyses revealed a high conservation of both the 5'- and 3'-untranslated regions but considerable divergence within the open reading frame. We also showed that ILHV displays a typical flavivirus structural and genomic organization. Our work lays the foundation for subsequent ILHV studies to better understand its transmission cycles, pathogenicity, and emergence potential.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Aedes
/
Culex
/
Flavivirus
País/Región como asunto:
America do sul
Idioma:
En
Revista:
Viruses
Año:
2023
Tipo del documento:
Article