A "biphasic glycosyltransferase high-throughput screen" identifies novel anthraquinone glycosides in the diversification of phenolic natural products.

Mohideen, F Ifthiha; Kwan, David H

Mohideen, F Ifthiha; Kwan, David H.

Afiliación

Mohideen FI; Department of Biology, Centre for Applied Synthetic Biology, and Centre for Structural and Functional Genomics, Concordia University, Montreal, Quebec, Canada.
Kwan DH; Department of Biology, Centre for Applied Synthetic Biology, and Centre for Structural and Functional Genomics, Concordia University, Montreal, Quebec, Canada; Department of Chemistry and Biochemistry, Concordia University, Montreal, Quebec, Canada; PROTEO, Quebec Network for Research on Protein Function, Quebec City, Quebec, Canada. Electronic address: david.kwan@concordia.ca.

J Biol Chem ; 299(3): 102931, 2023 03.

Article en En | MEDLINE | ID: mdl-36682498

Asunto(s)

Productos Biológicos; Descubrimiento de Drogas; Glicósidos; Glicosiltransferasas; Antraquinonas/química; Productos Biológicos/química; Glicósidos/síntesis química; Glicósidos/aislamiento & purificación; Glicosiltransferasas/metabolismo; Azúcares; Ensayos Analíticos de Alto Rendimiento; Descubrimiento de Drogas/métodos

Palabras clave

combinatorial enzymatic synthesis; glycodiversification; glycosylation; glycosyltransferases; high-throughput screening; natural products

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Productos Biológicos / Glicosiltransferasas / Descubrimiento de Drogas / Glicósidos Idioma: En Revista: J Biol Chem Año: 2023 Tipo del documento: Article

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