Distinctive transcriptomic and epigenomic signatures of bone marrow-derived myeloid cells and microglia in CNS autoimmunity.

Manouchehri, Navid; Salinas, Victor H; Hussain, Rehana Z; Stüve, Olaf

Manouchehri, Navid; Salinas, Victor H; Hussain, Rehana Z; Stüve, Olaf.

Afiliación

Manouchehri N; Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Salinas VH; Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Hussain RZ; Neurology Section, Veterans Affairs North Texas Health Care System, Dallas, TX 75216.
Stüve O; Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX 75390.

Proc Natl Acad Sci U S A ; 120(6): e2212696120, 2023 02 07.

Article en En | MEDLINE | ID: mdl-36730207

Asunto(s)

Encefalomielitis Autoinmune Experimental; Microglía; Ratones; Humanos; Animales; Microglía/metabolismo; Médula Ósea/metabolismo; Autoinmunidad/genética; Transcriptoma; Epigenómica; Ratones Endogámicos C57BL; Sistema Nervioso Central; Células Mieloides/metabolismo

Palabras clave

experimental autoimmune encephalomyelitis; microglia; multiple sclerosis; myeloid cells; transcriptomics

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Microglía / Encefalomielitis Autoinmune Experimental Tipo de estudio: Prognostic_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article

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