The Caprini Risk Score for Early Prediction of Mortality in Patients With Acute Coronary Syndrome.
J Cardiovasc Nurs
; 38(5): 472-480, 2023.
Article
en En
| MEDLINE
| ID: mdl-36730880
ABSTRACT
BACKGROUND:
The Caprini Risk Score (CRS) is a validated predictive instrument for venous thrombosis. Previous investigators have shown that a high CRS is associated with a higher risk of mortality from thrombotic diseases.OBJECTIVE:
The aim of this study was to assess the association between the CRS and prognosis of patients with acute coronary syndrome (ACS).METHODS:
Secondary analysis of data from a retrospective cohort study was conducted. Patients were classified into 3 CRS-based categories (CRS ≤ 2, CRS = 3-4, and CRS ≥ 5, indicating low, medium, and high, respectively). Kaplan-Meier curves and Cox regression models were used to assess the prognosis of patients with ACS. All-cause mortality and cardiac mortality were the end points.RESULTS:
Two hundred fifty-four patients (12.8%) died during follow-up. Multivariate Cox regression models identified CRS as an independent risk factor for all-cause mortality among patients with ACS (CRS = 3-4 vs CRS ≤ 2, hazard ratio 3.268, 95% confidence interval 1.396-7.647, P = .006; CRS ≥ 5 vs CRS ≤ 2, hazard ratio 4.099, 95% confidence interval 1.708-9.841, P = .002). Pearson correlation analysis showed a positive correlation between CRS and fibrinogen level ( r = 0.486, R2 = 0.765, P < .001) as well as D-dimer level ( r = 0.480, R2 = 0.465, P < .001).CONCLUSION:
The CRS is a useful prognostic assessment instrument for patients with ACS, and the risk stratification of patients with ACS can be achieved based on their CRS at admission.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Síndrome Coronario Agudo
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Revista:
J Cardiovasc Nurs
Asunto de la revista:
ANGIOLOGIA
/
CARDIOLOGIA
/
ENFERMAGEM
Año:
2023
Tipo del documento:
Article