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Fructose Induced KHK-C Increases ER Stress and Modulates Hepatic Transcriptome to Drive Liver Disease in Diet-Induced and Genetic Models of NAFLD.
Park, Se-Hyung; Helsley, Robert N; Fadhul, Taghreed; Willoughby, Jennifer L S; Noetzli, Leila; Tu, Ho-Chou; Solheim, Marie H; Fujisaka, Shiho; Pan, Hui; Dreyfuss, Jonathan M; Bons, Joanna; Rose, Jacob; King, Christina D; Schilling, Birgit; Lusis, Aldons J; Pan, Calvin; Gupta, Manoj; Kulkarni, Rohit N; Fitzgerald, Kevin; Kern, Philip A; Divanovic, Senad; Kahn, C Ronald; Softic, Samir.
Afiliación
  • Park SH; Department of Pediatrics, Division of Pediatric Gastroenterology, University of Kentucky College of Medicine, Lexington, KY. 40536.
  • Helsley RN; Department of Pediatrics, Division of Pediatric Gastroenterology, University of Kentucky College of Medicine, Lexington, KY. 40536.
  • Fadhul T; Department of Pediatrics, Division of Pediatric Gastroenterology, University of Kentucky College of Medicine, Lexington, KY. 40536.
  • Willoughby JLS; Alnylam Pharmaceuticals Inc., Cambridge, MA. 02142.
  • Noetzli L; Alnylam Pharmaceuticals Inc., Cambridge, MA. 02142.
  • Tu HC; Alnylam Pharmaceuticals Inc., Cambridge, MA. 02142.
  • Solheim MH; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA. 02215.
  • Fujisaka S; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, 50931 Cologne, Germany.
  • Pan H; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA. 02215.
  • Dreyfuss JM; First Department of Internal Medicine, University of Toyama, Toyama 930-0194, Japan.
  • Bons J; Bioinformatics and Biostatistics Core, Joslin Diabetes Center, Harvard Medical School, Boston, MA.
  • Rose J; Bioinformatics and Biostatistics Core, Joslin Diabetes Center, Harvard Medical School, Boston, MA.
  • King CD; Proteomics and Aging Center, Buck Institute for Research on Aging, Novato, CA 94945.
  • Schilling B; Proteomics and Aging Center, Buck Institute for Research on Aging, Novato, CA 94945.
  • Lusis AJ; Proteomics and Aging Center, Buck Institute for Research on Aging, Novato, CA 94945.
  • Pan C; Proteomics and Aging Center, Buck Institute for Research on Aging, Novato, CA 94945.
  • Gupta M; Department of Medicine/Division of Cardiology, Department of Human Genetics, A2-237 Center for the Health Sciences, University of California, Los Angeles, Los Angeles, CA USA.
  • Kulkarni RN; Department of Medicine/Division of Cardiology, Department of Human Genetics, A2-237 Center for the Health Sciences, University of California, Los Angeles, Los Angeles, CA USA.
  • Fitzgerald K; Section of Islet Cell and Regenerative Biology, Joslin Diabetes Center; Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02215.
  • Kern PA; Section of Islet Cell and Regenerative Biology, Joslin Diabetes Center; Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02215.
  • Divanovic S; Alnylam Pharmaceuticals Inc., Cambridge, MA. 02142.
  • Kahn CR; Department of Medicine, Division of Endocrinology, University of Kentucky College of Medicine, Lexington, KY. 40536.
  • Softic S; Department of Pediatrics, University of Cincinnati College of Medicine, Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.
bioRxiv ; 2023 Jan 27.
Article en En | MEDLINE | ID: mdl-36747758
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Texto completo: 1 Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: BioRxiv Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: BioRxiv Año: 2023 Tipo del documento: Article