Evolutionary dynamics and adaptive benefits of deleterious mutations in crop gene pools.
Trends Plant Sci
; 28(6): 685-697, 2023 06.
Article
en En
| MEDLINE
| ID: mdl-36764870
ABSTRACT
Mutations with deleterious consequences in nature may be conditionally deleterious in crop plants. That is, while some genetic variants may reduce fitness under wild conditions and be subject to purifying selection, they can be under positive selection in domesticates. Such deleterious alleles can be plant breeding targets, particularly for complex traits. The difficulty of distinguishing favorable from unfavorable variants reduces the power of selection, while favorable trait variation and heterosis may be attributable to deleterious alleles. Here, we review the roles of deleterious mutations in crop breeding and discuss how they can be used as a new avenue for crop improvement with emerging genomic tools, including HapMaps and pangenome analysis, aiding the identification, removal, or exploitation of deleterious mutations.
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Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Evolución Biológica
/
Pool de Genes
Idioma:
En
Revista:
Trends Plant Sci
Asunto de la revista:
BOTANICA
Año:
2023
Tipo del documento:
Article