Periostin secreted from podoplanin-positive cancer-associated fibroblasts promotes metastasis of gastric cancer by regulating cancer stem cells via AKT and YAP signaling pathway.

Zhao, Zhenxiong; Zhang, Yanqiu; Guo, Ergang; Zhang, Yu; Wang, Yanong

Zhao, Zhenxiong; Zhang, Yanqiu; Guo, Ergang; Zhang, Yu; Wang, Yanong.

Afiliación

Zhao Z; Department of Gastric Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Zhang Y; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Guo E; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Zhang Y; Department of Gastrointestinal Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Wang Y; Department of Oncology, Tongji HospitalTongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Mol Carcinog ; 62(5): 685-699, 2023 05.

Article en En | MEDLINE | ID: mdl-36785937

Asunto(s)

Fibroblastos Asociados al Cáncer; Neoplasias Gástricas; Animales; Fibroblastos Asociados al Cáncer/patología; Proteínas Proto-Oncogénicas c-akt/metabolismo; Neoplasias Gástricas/patología; Fosfatidilinositol 3-Quinasas/metabolismo; Tomografía Computarizada por Tomografía de Emisión de Positrones; Transducción de Señal; Células Madre Neoplásicas/metabolismo; Microambiente Tumoral; Fibroblastos/metabolismo

Palabras clave

PI3K/AKT pathway; cancer stem cell; cancer-associated fibroblast; periostin; podoplanin

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Gástricas / Fibroblastos Asociados al Cáncer Tipo de estudio: Risk_factors_studies Idioma: En Revista: Mol Carcinog Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2023 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google