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Screening for DAX1/EWS-FLI1 functional inhibitors identified dihydroorotate dehydrogenase as a therapeutic target for Ewing's sarcoma.
Watanabe, Miwa; Kosaka, Hiromichi; Sugawara, Masamori; Maemoto, Michihiro; Ono, Yoko; Uemori, Takeshi; Shizu, Ryota; Yoshinari, Kouichi.
Afiliación
  • Watanabe M; Research and Development Division, Kyowa Kirin Co., Ltd., Shizuoka, Japan.
  • Kosaka H; Department of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
  • Sugawara M; Research and Development Division, Kyowa Kirin Co., Ltd., Shizuoka, Japan.
  • Maemoto M; Research and Development Division, Kyowa Kirin Co., Ltd., Shizuoka, Japan.
  • Ono Y; Research and Development Division, Kyowa Kirin Co., Ltd., Shizuoka, Japan.
  • Uemori T; Research and Development Division, Kyowa Kirin Co., Ltd., Shizuoka, Japan.
  • Shizu R; Research and Development Division, Kyowa Kirin Co., Ltd., Shizuoka, Japan.
  • Yoshinari K; Department of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
Cancer Med ; 12(8): 9802-9814, 2023 04.
Article en En | MEDLINE | ID: mdl-36825574
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Sarcoma de Ewing Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Idioma: En Revista: Cancer Med Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Sarcoma de Ewing Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Idioma: En Revista: Cancer Med Año: 2023 Tipo del documento: Article