Ritonavir-boosted Nirmatrelvir and COVID-19 outcomes in the age of Omicron variant.
Ann Med Surg (Lond)
; 85(2): 313-315, 2023 Feb.
Article
en En
| MEDLINE
| ID: mdl-36845759
ABSTRACT
Nirmatrelvir boosted with Ritonavir is the recommended and preferred treatment for COVID-19. Because real-world evidence of Nirmatrelvir's antiviral activity against the Omicron variation is minimal, our study focuses on recent papers suggesting the use of Ritonavir-boosted Nirmatrelvir in the real world against the most frequent SARS coronavirus variant circulating worldwide (Omicron). Despite sparse clinical evidence, we discovered that Ritonavir-boosted Nirmatrelvir reduced COVID-19-related hospitalization and mortality during the onset of the Omicron variant. Furthermore, this study discusses the main limitations and offers recommendations for administering this drug in non-hospitalized COVID-19 patients at high risk for severe infection.
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MEDLINE
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Guideline
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En
Revista:
Ann Med Surg (Lond)
Año:
2023
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Article