Therapeutic targeting of vascular malformation in a zebrafish model of hereditary haemorrhagic telangiectasia.

Snodgrass, Ryan O; Govindpani, Karan; Plant, Karen; Kugler, Elisabeth C; Doh, Changmin; Dawson, Thomas; McCormack, Luis E; Arthur, Helen M; Chico, Timothy J A

Snodgrass, Ryan O; Govindpani, Karan; Plant, Karen; Kugler, Elisabeth C; Doh, Changmin; Dawson, Thomas; McCormack, Luis E; Arthur, Helen M; Chico, Timothy J A.

Afiliación

Snodgrass RO; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, UK.
Govindpani K; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, UK.
Plant K; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, UK.
Kugler EC; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, UK.
Doh C; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, UK.
Dawson T; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, UK.
McCormack LE; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, UK.
Arthur HM; Biosciences Institute, Centre for Life, Newcastle University, Newcastle NE1 3BZ, UK.
Chico TJA; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, UK.

Dis Model Mech ; 16(4)2023 04 01.

Article en En | MEDLINE | ID: mdl-36861761

Asunto(s)

Malformaciones Arteriovenosas; Telangiectasia Hemorrágica Hereditaria; Animales; Telangiectasia Hemorrágica Hereditaria/tratamiento farmacológico; Telangiectasia Hemorrágica Hereditaria/genética; Pez Cebra/metabolismo; Endoglina/genética; Factor A de Crecimiento Endotelial Vascular/genética; Malformaciones Arteriovenosas/genética; Serina-Treonina Quinasas TOR; Quinasas de Proteína Quinasa Activadas por Mitógenos/genética; Receptores de Activinas Tipo II/genética; Mutación/genética

Palabras clave

Angiogenesis; Endoglin; HHT; VEGF; Zebrafish

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Malformaciones Arteriovenosas / Telangiectasia Hemorrágica Hereditaria Tipo de estudio: Prognostic_studies Idioma: En Revista: Dis Model Mech Asunto de la revista: MEDICINA Año: 2023 Tipo del documento: Article

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