Evaluations of the neuroprotective effects of a dual-target isoquinoline inhibitor in the triple transgenic mouse model of Alzheimer's disease.

Wei, Rong; He, Jun-Qiu; Chen, Wen-Hua; Tam, Kin Yip

Wei, Rong; He, Jun-Qiu; Chen, Wen-Hua; Tam, Kin Yip.

Afiliación

Wei R; School of Biotechnology and Health Sciences, Wuyi University, Jiangmen, Guangdong 529020, PR China.
He JQ; Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, PR China.
Chen WH; School of Biotechnology and Health Sciences, Wuyi University, Jiangmen, Guangdong 529020, PR China. Electronic address: whchen@wyu.edu.cn.
Tam KY; Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, PR China. Electronic address: kintam@um.edu.mo.

Neurosci Lett ; 802: 137166, 2023 04 01.

Article en En | MEDLINE | ID: mdl-36889377

Asunto(s)

Enfermedad de Alzheimer; Neuroblastoma; Fármacos Neuroprotectores; Ratones; Humanos; Femenino; Animales; Enfermedad de Alzheimer/patología; Ratones Transgénicos; Fármacos Neuroprotectores/farmacología; Fármacos Neuroprotectores/uso terapéutico; Glucógeno Sintasa Quinasa 3 beta; Neuroblastoma/tratamiento farmacológico; Péptidos beta-Amiloides; Isoquinolinas/uso terapéutico; Modelos Animales de Enfermedad; Proteínas Represoras

Palabras clave

Alzheimer's disease; Amyloid plaque; Apoptosis; Dual-target inhibitor; Early stage disease

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Fármacos Neuroprotectores / Enfermedad de Alzheimer / Neuroblastoma Tipo de estudio: Prognostic_studies Idioma: En Revista: Neurosci Lett Año: 2023 Tipo del documento: Article

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