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Heterobifunctional Ligase Recruiters Enable pan-Degradation of Inhibitor of Apoptosis Proteins.
Ng, Yuen Lam Dora; Bricelj, Alesa; Jansen, Jacqueline A; Murgai, Arunima; Peter, Kirsten; Donovan, Katherine A; Gütschow, Michael; Krönke, Jan; Steinebach, Christian; Sosic, Izidor.
Afiliación
  • Ng YLD; Department of Hematology, Oncology and Cancer Immunology, Charité─Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, D-12203 Berlin, Germany.
  • Bricelj A; Faculty of Pharmacy, University of Ljubljana, Askerceva Cesta 7, SI-1000 Ljubljana, Slovenia.
  • Jansen JA; Department of Hematology, Oncology and Cancer Immunology, Charité─Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, D-12203 Berlin, Germany.
  • Murgai A; Department of Hematology, Oncology and Cancer Immunology, Charité─Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, D-12203 Berlin, Germany.
  • Peter K; German Cancer Consortium (DKTK) Partner Site Berlin and German Cancer Research Center (DKFZ), D-69120 Heidelberg, Germany.
  • Donovan KA; Department of Hematology, Oncology and Cancer Immunology, Charité─Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, D-12203 Berlin, Germany.
  • Gütschow M; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.
  • Krönke J; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02215, United States.
  • Steinebach C; Phamaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany.
  • Sosic I; Department of Hematology, Oncology and Cancer Immunology, Charité─Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, D-12203 Berlin, Germany.
J Med Chem ; 66(7): 4703-4733, 2023 04 13.
Article en En | MEDLINE | ID: mdl-36996313

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Inhibidoras de la Apoptosis / Neoplasias Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Inhibidoras de la Apoptosis / Neoplasias Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article