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CRISPR/Cas9-engineering of HMC-1.2 cells renders a human mast cell line with a single D816V-KIT mutation: An improved preclinical model for research on mastocytosis.
Bandara, Geethani; Falduto, Guido H; Luker, Andrea; Bai, Yun; Pfeiffer, Annika; Lack, Justin; Metcalfe, Dean D; Olivera, Ana.
Afiliación
  • Bandara G; Mast Cell Biology Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
  • Falduto GH; Mast Cell Biology Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
  • Luker A; Mast Cell Biology Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
  • Bai Y; Mast Cell Biology Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
  • Pfeiffer A; Mast Cell Biology Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
  • Lack J; National Institute of Allergy and Infectious Diseases (NIAID), Collaborative Bioinformatics Resource (NCBR), National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
  • Metcalfe DD; Mast Cell Biology Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
  • Olivera A; Mast Cell Biology Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Front Immunol ; 14: 1078958, 2023.
Article en En | MEDLINE | ID: mdl-37025992
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Mastocitosis / Mastocitosis Sistémica Tipo de estudio: Prognostic_studies Idioma: En Revista: Front Immunol Año: 2023 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Mastocitosis / Mastocitosis Sistémica Tipo de estudio: Prognostic_studies Idioma: En Revista: Front Immunol Año: 2023 Tipo del documento: Article