PROTAC antibiotics: the time is now.

Sarathy, Jickky Palmae; Aldrich, Courtney C; Go, Mei-Lin; Dick, Thomas

Sarathy, Jickky Palmae; Aldrich, Courtney C; Go, Mei-Lin; Dick, Thomas.

Afiliación

Sarathy JP; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA.
Aldrich CC; Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.
Go ML; Department of Chemistry and Department of Pharmacy, National University of Singapore, Singapore.
Dick T; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA.

Expert Opin Drug Discov ; 18(4): 363-370, 2023 04.

Article en En | MEDLINE | ID: mdl-37027333

Asunto(s)

Antibacterianos; Ubiquitina-Proteína Ligasas; Humanos; Antibacterianos/farmacología; Ubiquitina-Proteína Ligasas/metabolismo; Proteolisis

Palabras clave

Antibacterial drug discovery; proteolysis targeting chimeras; targeted protein degradation

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Ubiquitina-Proteína Ligasas / Antibacterianos Idioma: En Revista: Expert Opin Drug Discov Año: 2023 Tipo del documento: Article

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